Modifying Gene Expression Programs by Altering Core Promoter Chromatin Architecture
نویسندگان
چکیده
منابع مشابه
Modifying Gene Expression Programs by Altering Core Promoter Chromatin Architecture
Transcriptional activation of the IFN-beta gene in response to virus infection requires the assembly of an enhanceosome, which instructs a recruitment program of chromatin modifiers/remodelers and general transcription factors to the promoter. This program culminates with sliding of a nucleosome blocking the core promoter to a downstream position, a prerequisite for transcriptional activation. ...
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ژورنال
عنوان ژورنال: Cell
سال: 2002
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(02)00822-x